The Prox1 Rabbit Monoclonal Antibody (CAB9047) is a cutting-edge tool for researchers studying the Prox1 protein, a key regulator of developmental processes and cell differentiation. This antibody, produced in rabbits, exhibits exceptional reactivity with human samples and has been rigorously validated for use in various research applications, including immunohistochemistry and immunofluorescence.Prox1 is a transcription factor that plays a crucial role in the formation of lymphatic vessels, the development of the central nervous system, and the regulation of cell fate determination. Dysregulation of Prox1 expression has been linked to various diseases, including cancer and cardiovascular disorders, making it an attractive target for therapeutic intervention.
By utilizing the Prox1 Rabbit Monoclonal Antibody (CAB9047), researchers can effectively detect and analyze Prox1 protein levels in different cell types and tissues, opening up new avenues for exploration in developmental biology, cancer research, and regenerative medicine. Understanding the intricate functions of Prox1 is essential for unraveling the complex mechanisms underlying disease pathology and developing targeted therapies to combat them.
Product Name:
PROX1 Rabbit Monoclonal Antibody
SKU:
CAB9047
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human PROX1 (Q92786).
The protein encoded by this gene is a member of the homeobox transcription factor family. Members of this family contain a homeobox domain that consists of a 60-amino acid helix-turn-helix structure that binds DNA and RNA. The protein encoded by this gene is conserved across vertebrates and may play an essential role during development. Altered levels of this protein have been reported in cancers of different organs, such as colon, brain, blood, breast, pancreas, liver and esophagus. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
5629
Clone Number:
ARC1391
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates using PROX1 Rabbit mAb (CAB9047) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1min.
