The Prox1 Polyclonal Antibody (CAB13042) is a valuable tool for researchers studying Prox1, a key transcription factor involved in various cellular processes such as embryonic development, lymphatic vessel development, and organogenesis. This antibody, raised in rabbits, exhibits high reactivity with human samples and has been validated for use in applications such as immunohistochemistry and flow cytometry.Prox1 plays a crucial role in the regulation of gene expression and cell differentiation, making it a focal point in developmental biology and cancer research. Its involvement in lymphatic vessel formation also makes it a potential therapeutic target for conditions related to lymphatic dysfunction.
By using the Prox1 Polyclonal Antibody, researchers can detect and analyze Prox1 expression in different cell types, providing valuable insights into its function and potential clinical applications.Overall, the Prox1 Polyclonal Antibody is an essential tool for investigating the role of Prox1 in various physiological and pathological processes, contributing to the advancement of our understanding of development, disease, and potential therapeutic strategies.
Product Name:
PROX1 Rabbit Polyclonal Antibody
SKU:
CAB13042
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 220-375 of human PROX1 (NP_002754.2).
The protein encoded by this gene is a member of the homeobox transcription factor family. Members of this family contain a homeobox domain that consists of a 60-amino acid helix-turn-helix structure that binds DNA and RNA. The protein encoded by this gene is conserved across vertebrates and may play an essential role during development. Altered levels of this protein have been reported in cancers of different organs, such as colon, brain, blood, breast, pancreas, liver and esophagus. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
5629
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using PROX1 Rabbit pAb (CAB13042) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
