The Protocadherin 17 Polyclonal Antibody (CAB10512) is specifically designed for research involving Protocadherin 17, a cell surface protein that plays a key role in cell-cell adhesion and communication. This antibody, raised in rabbits, exhibits high reactivity with human samples and has been validated for use in various research applications, including Western blotting.Protocadherin 17 is known for its involvement in neuronal development and differentiation, making it a valuable target for studies in neuroscience and developmental biology. By binding to the Protocadherin 17 protein, this antibody enables precise detection and analysis of this important molecule in different cell types and tissues.
The functional implications of Protocadherin 17 in cellular interactions and signaling pathways make it a promising candidate for research into various physiological and pathological processes. Understanding the role of Protocadherin 17 is essential for unraveling its contributions to biological functions and diseases, offering potential insights for therapeutic strategies in conditions such as neurodevelopmental disorders and cancer.
Product Name:
PCDH17 Rabbit Polyclonal Antibody
SKU:
CAB10512
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 610-710 of human PCDH17 (NP_001035519.1).
Cell membrane, Single-pass type I membrane protein.
Calculated MW:
126kDa
Observed MW:
150kDa
This gene belongs to the protocadherin gene family, a subfamily of the cadherin superfamily. The encoded protein contains six extracellular cadherin domains, a transmembrane domain, and a cytoplasmic tail differing from those of the classical cadherins. The encoded protein may play a role in the establishment and function of specific cell-cell connections in the brain.
Purification Method:
Affinity purification
Gene ID:
27253
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of lysates from 293T cells, using PCDH17 Rabbit pAb (CAB10512) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 60s.
