PCDH15 Rabbit Polyclonal Antibody (CAB10086)
- SKU:
- CAB10086
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | PCDH15 Rabbit Polyclonal Antibody |
SKU: | CAB10086 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 160-400 of human PCDH15 (NP_001136235.1). |
Sequence: | TVNE LTPV GTTI FTGF SGDN GATD IDDG PNGQ IEYV IQYN PDDP TSND TFEI PLML TGNI VLRK RLNY EDKT RYFV IIQA NDRA QNLN ERRT TTTT LTVD VLDG DDLG PMFL PCVL VPNT RDCR PLTY QAAI PELR TPEE LNPI IVTP PIQA IDQD RNIQ PPSD RPGI LYSI LVGT PEDY PRFF HMHP RTAE LSLL EPVN RDFH QKFD LVIK AEQD NGHP LPAF AGLH IEIL DENN QSPY F |
Tested Applications: | WB IHC-P ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IHC-P,1:100 - 1:200 |
Synonyms: | USH1F; CDHR15; DFNB23; PCDH15 |
Positive Sample: | SH-SY5Y,293T,A-549,Raji,Mouse brain,Mouse liver,Mouse spleen,Rat brain,Rat liver |
Conjugate: | Unconjugated |
Cellular Localization: | Cell membrane, Secreted, Single-pass type I membrane protein. |
Calculated MW: | 216kDa |
Observed MW: | 100kDa |
This gene is a member of the cadherin superfamily. Family members encode integral membrane proteins that mediate calcium-dependent cell-cell adhesion. It plays an essential role in maintenance of normal retinal and cochlear function. Mutations in this gene result in hearing loss and Usher Syndrome Type IF (USH1F). Extensive alternative splicing resulting in multiple isoforms has been observed in the mouse ortholog. Similar alternatively spliced transcripts are inferred to occur in human, and additional variants are likely to occur.
Purification Method: | Affinity purification |
Gene ID: | 65217 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |