The WNT-7A Polyclonal Antibody (CAB5425) is a valuable tool for researchers studying the WNT-7A protein, a key player in the WNT signaling pathway involved in various cellular processes, including embryonic development and cancer progression. This antibody, produced in rabbits, exhibits high reactivity with human samples and is validated for use in Western blot applications.By binding specifically to the WNT-7A protein, this antibody enables accurate detection and analysis in a variety of cell types, making it an ideal choice for studies in developmental biology, cancer research, and regenerative medicine.
Understanding the role of WNT-7A in these processes is essential for identifying potential therapeutic targets and developing innovative treatments for diseases such as cancer and developmental disorders. Overall, the WNT-7A Polyclonal Antibody offers researchers a reliable and specific tool for investigating the intricate mechanisms of the WNT signaling pathway and its implications in various physiological and pathological conditions.
Product Name:
WNT7A Rabbit Polyclonal Antibody
SKU:
CAB5425
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 101-200 of human WNT7A (NP_004616.2).
This gene is a member of the WNT gene family, which consists of structurally related genes that encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is involved in the development of the anterior-posterior axis in the female reproductive tract, and also plays a critical role in uterine smooth muscle pattering and maintenance of adult uterine function. Mutations in this gene are associated with Fuhrmann and Al-Awadi/Raas-Rothschild/Schinzel phocomelia syndromes.
Purification Method:
Affinity purification
Gene ID:
7476
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.09% Sodium azide,50% glycerol,pH7.3.
Western blot analysis of lysates from BeWo cells, using WNT7A Rabbit pAb (CAB5425) at 1:500 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 180s.
