WNT5A Rabbit Polyclonal Antibody (CAB2133)
- SKU:
- CAB2133
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Description
Product Name: | WNT5A Rabbit Polyclonal Antibody |
SKU: | CAB2133 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 65-305 of human WNT5A (NP_003383.2). |
Sequence: | AQPL CSQL AGLS QGQK KLCH LYQD HMQY IGEG AKTG IKEC QYQF RHRR WNCS TVDN TSVF GRVM QIGS RETA FTYA VSAA GVVN AMSR ACRE GELS TCGC SRAA RPKD LPRD WLWG GCGD NIDY GYRF AKEF VDAR ERER IHAK GSYE SARI LMNL HNNE AGRR TVYN LADV ACKC HGVS GSCS LKTC WLQL ADFR KVGD ALKE KYDS AAAM RLNS RGKL VQVN SRFN SPTT QDLV YIDP S |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 |
Synonyms: | hWNT5A; WNT5A |
Positive Sample: | Mouse brain |
Conjugate: | Unconjugated |
Cellular Localization: | Secreted, extracellular matrix, extracellular space. |
Calculated MW: | 42kDa |
Observed MW: | 42kDa |
The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene encodes a member of the WNT family that signals through both the canonical and non-canonical WNT pathways. This protein is a ligand for the seven transmembrane receptor frizzled-5 and the tyrosine kinase orphan receptor 2. This protein plays an essential role in regulating developmental pathways during embryogenesis. This protein may also play a role in oncogenesis. Mutations in this gene are the cause of autosomal dominant Robinow syndrome. Alternate splicing results in multiple transcript variants.
Purification Method: | Affinity purification |
Gene ID: | 7474 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |