The Wnt-3a Polyclonal Antibody (CAB0642) is a valuable tool for researchers studying the Wnt-3a protein, a key regulator of cell signaling pathways involved in development, tissue regeneration, and disease progression. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications, allowing for the detection and analysis of Wnt-3a protein expression in various cell types.Wnt-3a is known to play a critical role in cell proliferation, differentiation, and migration, making it a target of interest in studies focusing on developmental biology, stem cell research, and cancer biology.
Its dysregulation has been implicated in various diseases, including cancer, neurodegenerative disorders, and cardiovascular conditions, highlighting the importance of understanding Wnt-3a's function in health and disease states.By utilizing the Wnt-3a Polyclonal Antibody, researchers can investigate the role of Wnt-3a in cellular processes and disease pathways, providing insights that may lead to the development of novel therapeutic strategies targeting the Wnt signaling pathway. This antibody is a valuable tool for advancing research in fields such as oncology, regenerative medicine, and drug discovery.
Product Name:
WNT3A Rabbit Polyclonal Antibody
SKU:
CAB0642
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 100-200 of human WNT3A (NP_149122.1).
The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It encodes a protein which shows 96% amino acid identity to mouse Wnt3A protein, and 84% to human WNT3 protein, another WNT gene product. This gene is clustered with WNT14 gene, another family member, in chromosome 1q42 region.
Purification Method:
Affinity purification
Gene ID:
89780
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of U2OS, using WNT3A antibody (CAB0642) at 1:800 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 60s.
