The UXT Polyclonal Antibody (CAB4217) is a valuable tool for research involving the UXT protein, a key player in various cellular processes including transcriptional regulation and DNA repair. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By targeting the UXT protein, this antibody enables precise detection and analysis in a wide range of cell types, making it an essential asset for studies in molecular biology and cancer research.
UXT, also known as Ubiquitously eXpressed Transcript, plays a vital role in gene expression regulation and is involved in the maintenance of genomic stability. Its involvement in DNA repair mechanisms and cellular stress response makes it a promising target for investigating diseases such as cancer and neurodegenerative disorders. By studying the functions of UXT, researchers can gain valuable insights into the underlying molecular mechanisms of these diseases and potentially identify new therapeutic approaches.
Product Name:
UXT Rabbit Polyclonal Antibody
SKU:
CAB4217
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 13-169 of human UXT (NP_705582.1).
The protein encoded by this gene functions as a cofactor that modulates androgen receptor-dependent transcription, and also plays a critical role in tumor necrosis factor-induced apoptosis. Expression of this gene may play a role in tumorigenesis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Purification Method:
Affinity purification
Gene ID:
8409
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using UXT antibody (CAB4217) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
