The TMEPAI Polyclonal Antibody (CAB12171) is specifically designed for research involving TMEPAI, a protein involved in regulating cell proliferation and tumorigenesis. This antibody, raised in rabbits, is highly reactive with human samples and has been validated for use in Western blot applications.TMEPAI, also known as transmembrane prostate androgen-induced protein, is a critical regulator of cell growth and has been implicated in various cancer types. By targeting TMEPAI, researchers can study the mechanisms underlying cell proliferation and potentially develop targeted therapies for cancer treatment.
This antibody enables the detection and analysis of TMEPAI in different cell types, making it a valuable tool for studies in cancer research and cell biology. Understanding the function of TMEPAI is essential for unraveling its roles in tumorigenesis and identifying potential therapeutic targets for cancer treatment.
Product Name:
PMEPA1 Rabbit Polyclonal Antibody
SKU:
CAB12171
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 173-252 of human PMEPA1 (NP_954638.1).
Early endosome membrane, Golgi apparatus membrane, Single-pass membrane protein.
Calculated MW:
32kDa
Observed MW:
37kDa
This gene encodes a transmembrane protein that contains a Smad interacting motif (SIM). Expression of this gene is induced by androgens and transforming growth factor beta, and the encoded protein suppresses the androgen receptor and transforming growth factor beta signaling pathways though interactions with Smad proteins. Overexpression of this gene may play a role in multiple types of cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Purification Method:
Affinity purification
Gene ID:
56937
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using PMEPA1 Rabbit pAb (CAB12171) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
