The Protein TFG Polyclonal Antibody (CAB7769) is a highly specific research tool designed for studying the TFG protein, a key player in cellular trafficking and signaling pathways. This antibody, raised in rabbits, exhibits strong reactivity with human samples and has been validated for use in Western blot applications.TFG, also known as TRK-fused gene, is involved in regulating protein transport within cells and is important for maintaining cellular homeostasis. Dysregulation of TFG has been linked to various diseases, including cancer and neurodegenerative disorders, making it a promising target for therapeutic intervention.
By specifically binding to the TFG protein, this antibody enables precise detection and analysis in various cell types, making it an essential tool for researchers in the fields of cell biology, cancer research, and drug development. Understanding the role of TFG in cellular processes is crucial for advancing our knowledge of disease mechanisms and developing novel treatments targeting TFG-related pathways.
Product Name:
TRK fused gene (TFG) Rabbit Polyclonal Antibody
SKU:
CAB7769
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-240 of human TRK fused gene (TFG) (NP_006061.2).
cytoplasm, cytosol, endoplasmic reticulum exit site
Calculated MW:
43kDa
Observed MW:
43kDa
There are several documented fusion oncoproteins encoded partially by this gene. This gene also participates in several oncogenic rearrangements resulting in anaplastic lymphoma and mixoid chondrosarcoma, and may play a role in the NF-kappaB pathway. Multiple transcript variants have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
10342
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of lysates from SH-SY5Y cells using TRK fused gene (TFG) Rabbit pAb(CAB7769) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25 μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 5s.
