SSX2 Rabbit Polyclonal Antibody (CAB6989)
- SKU:
- CAB6989
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
Description
Product Name: | SSX2 Rabbit Polyclonal Antibody |
SKU: | CAB6989 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-188 of human SSX2 (NP_783629.1). |
Sequence: | MNGD DAFA RRPT VGAQ IPEK IQKA FDDI AKYF SKEE WEKM KASE KIFY VYMK RKYE AMTK LGFK ATLP PFMC NKRA EDFQ GNDL DNDP NRGN QVER PQMT FGRL QGIS PKIM PKKP AEEG NDSE EVPE ASGP QNDG KELC PPGK PTTS EKIH ERSG PKRG EHAW THRL RERK QLVI YEEI SDPE EDDE |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | SSX; HD21; CT5.2; CT5.2A; HOM-MEL-40; SSX2 |
Positive Sample: | HeLa |
Conjugate: | Unconjugated |
Cellular Localization: | Nucleus. |
Calculated MW: | 22kDa |
Observed MW: | 22kDa |
The product of this gene belongs to the family of highly homologous synovial sarcoma X (SSX) breakpoint proteins. These proteins may function as transcriptional repressors. They are also capable of eliciting spontaneous humoral and cellular immune responses in cancer patients, and are potentially useful targets in cancer vaccine-based immunotherapy. This gene, and also the SSX1 and SSX4 family members, have been involved in t(X;18)(p11.2;q11.2) translocations that are characteristically found in all synovial sarcomas. This translocation results in the fusion of the synovial sarcoma translocation gene on chromosome 18 to one of the SSX genes on chromosome X. The encoded hybrid proteins are likely responsible for transforming activity. Alternative splicing of this gene results in multiple transcript variants. This gene also has an identical duplicate, GeneID: 727837, located about 45 kb downstream in the opposite orientation on chromosome X.
Purification Method: | Affinity purification |
Gene ID: | 6757 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |