null

SET/TAF1 Rabbit Polyclonal Antibody (CAB6212)

SKU:
CAB6212
Product Type:
Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Immunology
  • Immunology Antibodies 2 Anti-SET Antibody CAB6212
  • Immunology Antibodies 2 Anti-SET Antibody CAB6212
  • Immunology Antibodies 2 Anti-SET Antibody CAB6212
  • Immunology Antibodies 2 Anti-SET Antibody CAB6212
  • Immunology Antibodies 2 Anti-SET Antibody CAB6212
€139 - €419
Frequently bought together:

Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:SET/TAF1 Rabbit Polyclonal Antibody
SKU:CAB6212
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human,Mouse,Rat
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-277 of human SET/TAF1 (NP_003002.2).
Sequence:MSAP AAKV SKKE LNSN HDGA DETS EKEQ QEAI EHID EVQN EIDR LNEQ ASEE ILKV EQKY NKLR QPFF QKRS ELIA KIPN FWVT TFVN HPQV SALL GEED EEAL HYLT RVEV TEFE DIKS GYRI DFYF DENP YFEN KVLS KEFH LNES GDPS SKST EIKW KSGK DLTK RSSQ TQNK ASRK RQHE EPES FFTW FTDH SDAG ADEL GEVI KDDI WPNP LQYY LVPD MDDE EGEG EEDD DDDE EEEG LEDI DEEG DEDE GEED EDDD EGEE GEED EGED D
Tested Applications:WB IHC-P IF/ICC ELISA
Recommended Dilution:WB,1:100 - 1:500 IHC-P,1:50 - 1:200 IF/ICC,1:50 - 1:200
Synonyms:2PP2A; IGAAD; MRD58; TAF-I; I2PP2A; IPP2A2; PHAPII; TAF-IBETA; SET/TAF1
Positive Sample:293T
Conjugate:Unconjugated
Cellular Localization:Cytoplasm, Endoplasmic reticulum, Nucleus, cytosol, nucleoplasm.
Calculated MW:33kDa
Observed MW:33kDa

The protein encoded by this gene inhibits acetylation of nucleosomes, especially histone H4, by histone acetylases (HAT). This inhibition is most likely accomplished by masking histone lysines from being acetylated, and the consequence is to silence HAT-dependent transcription. The encoded protein is part of a complex localized to the endoplasmic reticulum but is found in the nucleus and inhibits apoptosis following attack by cytotoxic T lymphocytes. This protein can also enhance DNA replication of the adenovirus genome. Several transcript variants encoding different isoforms have been found for this gene.

Purification Method:Affinity purification
Gene ID:6418
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Product ImageWestern blot analysis of lysates from 293T cells, using SET/TAF1 Rabbit pAb (CAB6212) at 1:500 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 180s.

Related Products