The Reprimo Polyclonal Antibody (CAB10013) is a valuable tool for researchers studying the Reprimo protein, a tumor suppressor involved in cell cycle regulation and DNA damage response. This antibody, produced in rabbits, exhibits high reactivity with human samples and is validated for use in Western blot applications. By targeting the Reprimo protein, this antibody enables accurate and specific detection in a variety of cell types, making it suitable for investigations in cancer biology and therapeutic research.
Reprimo is known for its role in controlling cell proliferation and promoting cell cycle arrest in response to DNA damage, serving as a key player in maintaining genomic stability and preventing tumor formation. Its dysregulation has been implicated in various cancers, making it a promising target for exploring new therapeutic strategies. By elucidating the functions of Reprimo, researchers can gain insights into tumor development mechanisms and potentially identify novel approaches for cancer treatment.
Product Name:
RPRM Rabbit Polyclonal Antibody
SKU:
CAB10013
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-109 of human RPRM (NP_062819.1).
Predicted to be involved in regulation of mitotic cell cycle. Predicted to act upstream of or within regulation of cell cycle. Predicted to be integral component of membrane. Predicted to be active in cytoplasm.
Purification Method:
Affinity purification
Gene ID:
56475
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of mouse pancreas, using RPRM antibody (CAB10013) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
