The Protein Phosphatase 1 Beta Rabbit Monoclonal Antibody (CAB4364) is a high-quality antibody designed for research involving Protein Phosphatase 1 Beta, an enzyme that plays a key role in cellular signaling and regulation. This antibody, raised in rabbits, is highly specific and reactive with human samples, providing reliable results in Western blot applications.Protein Phosphatase 1 Beta is involved in the dephosphorylation of various proteins, impacting processes such as cell cycle progression, gene expression, and metabolism. Dysregulation of this enzyme has been linked to diseases like cancer, diabetes, and neurodegenerative disorders, making it a valuable target for therapeutic interventions.
By using the Protein Phosphatase 1 Beta Rabbit Monoclonal Antibody (CAB4364), researchers can investigate the expression and activity of this enzyme in various cell types and tissues, advancing our understanding of its role in health and disease. This antibody is a valuable tool for studies in cellular signaling, molecular biology, and drug development, providing insights that could lead to new treatment strategies.
Product Name:
PP1 beta Rabbit Monoclonal Antibody
SKU:
CAB4364
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 228-327 of human PP1 beta (P62140).
The protein encoded by this gene is one of the three catalytic subunits of protein phosphatase 1 (PP1). PP1 is a serine/threonine specific protein phosphatase known to be involved in the regulation of a variety of cellular processes, such as cell division, glycogen metabolism, muscle contractility, protein synthesis, and HIV-1 viral transcription. Mouse studies suggest that PP1 functions as a suppressor of learning and memory. Two alternatively spliced transcript variants encoding distinct isoforms have been observed.
Purification Method:
Affinity purification
Gene ID:
5500
Clone Number:
ARC0981
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates using PP1 beta Rabbit mAb (CAB4364) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
