The NEDD1 Polyclonal Antibody (CAB5128) is a valuable tool for researchers studying NEDD1, a protein involved in the regulation of the centrosome, microtubule organization, and cell cycle progression. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blotting applications. By targeting the NEDD1 protein, this antibody allows for the detection and analysis of NEDD1 in a variety of cell types, making it an essential asset for studies in cell biology and cancer research.
NEDD1, also known as neural precursor cell expressed developmentally down-regulated protein 1, plays a crucial role in centrosome duplication and spindle assembly during cell division. Its involvement in microtubule organization and cell cycle control positions it as a key player in maintaining genomic stability and preventing the development of cancerous cells. Research into NEDD1 function is essential for understanding the mechanisms underlying cell division and identifying potential targets for anti-cancer therapies.
Product Name:
NEDD1 Rabbit Polyclonal Antibody
SKU:
CAB5128
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 411-660 of human NEDD1 (NP_690869.1).
Predicted to be involved in protein localization to centrosome. Located in centrosome; nucleoplasm; and plasma membrane.
Purification Method:
Affinity purification
Gene ID:
121441
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using NEDD1 antibody (CAB5128) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
