The NDRG2 Polyclonal Antibody (CAB5319) is a valuable tool for researchers studying N-myc downstream regulated gene 2 (NDRG2), a protein known for its role in cell growth, differentiation, and tumor suppression. This antibody, produced in rabbits, exhibits high specificity and sensitivity for detecting NDRG2 in human samples, making it ideal for various applications including Western blotting.NDRG2 is a tumor suppressor gene that is downregulated in multiple types of cancer, suggesting its potential as a therapeutic target for cancer treatment. By using the NDRG2 Polyclonal Antibody, researchers can study the expression and function of NDRG2 in different cell types and understand its mechanisms in cancer development and progression.
Furthermore, NDRG2 has been implicated in various cellular processes such as cell cycle regulation, metastasis, and response to cellular stress. Therefore, this antibody is a valuable tool for investigating the role of NDRG2 in normal physiological processes as well as in disease states. Its versatility and reliability make it an essential component for studies in cancer biology and potential drug development targeting NDRG2.
Product Name:
NDRG2 Rabbit Polyclonal Antibody
SKU:
CAB5319
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 138-357 of human NDRG2 (NP_963832.1).
This gene is a member of the N-myc downregulated gene family which belongs to the alpha/beta hydrolase superfamily. The protein encoded by this gene is a cytoplasmic protein that may play a role in neurite outgrowth. This gene may be involved in glioblastoma carcinogenesis. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
57447
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using NDRG2 antibody (CAB5319) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.
