The NDRG1 Polyclonal Antibody (CAB2142) is a valuable tool for researchers studying NDRG1, a protein involved in tumor suppression and cell differentiation. This antibody, produced in rabbits, is highly specific and reactive with human samples, making it ideal for use in Western blot applications. By binding to the NDRG1 protein, this antibody allows for the detection and analysis of NDRG1 expression in a variety of cell types.NDRG1, also known as N-myc downstream-regulated gene 1, is a key player in cellular processes such as cell growth, differentiation, and stress response. Its dysregulation has been implicated in various cancers, making it a potential target for cancer therapy and diagnosis.
By studying NDRG1 expression and function, researchers can gain insight into the mechanisms underlying tumorigenesis and potentially identify novel therapeutic strategies.Overall, the NDRG1 Polyclonal Antibody (CAB2142) is a valuable tool for researchers interested in unraveling the role of NDRG1 in cancer biology and other cellular processes. Its high specificity and sensitivity make it a reliable option for studying NDRG1 expression and function in a research setting.
Product Name:
NDRG1 Rabbit Polyclonal Antibody
SKU:
CAB2142
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 175-394 of human NDRG1 (NP_001128714.1).
This gene is a member of the N-myc downregulated gene family which belongs to the alpha/beta hydrolase superfamily. The protein encoded by this gene is a cytoplasmic protein involved in stress responses, hormone responses, cell growth, and differentiation. The encoded protein is necessary for p53-mediated caspase activation and apoptosis. Mutations in this gene are a cause of Charcot-Marie-Tooth disease type 4D, and expression of this gene may be a prognostic indicator for several types of cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Purification Method:
Affinity purification
Gene ID:
10397
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of extracts of U-87MG cells, using NDRG1 antibody (CAB2142) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
