NDRG1 Rabbit Polyclonal Antibody (CAB2142)
- SKU:
- CAB2142
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | NDRG1 Rabbit Polyclonal Antibody |
SKU: | CAB2142 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 175-394 of human NDRG1 (NP_001128714.1). |
Sequence: | WAAS KISG WTQA LPDM VVSH LFGK EEMQ SNVE VVHT YRQH IVND MNPG NLHL FINA YNSR RDLE IERP MPGT HTVT LQCP ALLV VGDS SPAV DAVV ECNS KLDP TKTT LLKM ADCG GLPQ ISQP AKLA EAFK YFVQ GMGY MPSA SMTR LMRS RTAS GSSV TSLD GTRS RSHT SEGT RSRS HTSE GTRS RSHT SEGA HLDI TPNS GAAG NSAG PKSM EVSC |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IF/ICC,1:50 - 1:200 |
Synonyms: | GC4; RTP; DRG1; NDR1; NMSL; TDD5; CAP43; CMT4D; DRG-1; HMSNL; RIT42; TARG1; PROXY1; G1 |
Positive Sample: | U-87MG,RAW264.7 |
Conjugate: | Unconjugated |
Cellular Localization: | Cell membrane, Cytoplasm, Nucleus, centrosome, cytoskeleton, cytosol, microtubule organizing center. |
Calculated MW: | 43kDa |
Observed MW: | 48kDa |
This gene is a member of the N-myc downregulated gene family which belongs to the alpha/beta hydrolase superfamily. The protein encoded by this gene is a cytoplasmic protein involved in stress responses, hormone responses, cell growth, and differentiation. The encoded protein is necessary for p53-mediated caspase activation and apoptosis. Mutations in this gene are a cause of Charcot-Marie-Tooth disease type 4D, and expression of this gene may be a prognostic indicator for several types of cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Purification Method: | Affinity purification |
Gene ID: | 10397 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |