MAX Rabbit Polyclonal Antibody (CAB2157)
- SKU:
- CAB2157
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
Product Name: | MAX Rabbit Polyclonal Antibody |
SKU: | CAB2157 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-160 of human MAX (NP_002373.3). |
Sequence: | MSDN DDIE VESD EEQP RFQS AADK RAHH NALE RKRR DHIK DSFH SLRD SVPS LQGE KASR AQIL DKAT EYIQ YMRR KNHT HQQD IDDL KRQN ALLE QQVR ALEK ARSS AQLQ TNYP SSDN SLYT NAKG STIS AFDG GSDS SSES EPEE PQSR KKLR MEAS |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | bHLHd4; MAX |
Positive Sample: | Mouse kidney |
Conjugate: | Unconjugated |
Cellular Localization: | Cell projection, Nucleus, dendrite. |
Calculated MW: | 18kDa |
Observed MW: | 19kDa |
The protein encoded by this gene is a member of the basic helix-loop-helix leucine zipper (bHLHZ) family of transcription factors. It is able to form homodimers and heterodimers with other family members, which include Mad, Mxi1 and Myc. Myc is an oncoprotein implicated in cell proliferation, differentiation and apoptosis. The homodimers and heterodimers compete for a common DNA target site (the E box) and rearrangement among these dimer forms provides a complex system of transcriptional regulation. Mutations of this gene have been reported to be associated with hereditary pheochromocytoma. A pseudogene of this gene is located on the long arm of chromosome 7. Alternative splicing results in multiple transcript variants.
Purification Method: | Affinity purification |
Gene ID: | 4149 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |