Phospho-MAX-S11 Rabbit Polyclonal Antibody (CABP0072)
- SKU:
- CABP0072
- Product Type:
- Antibody
- Applications:
- WB
- IF
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
Product Name: | Phospho-MAX-S11 Rabbit Polyclonal Antibody |
SKU: | CABP0072 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human |
Immunogen: | A synthetic phosphorylated peptide around S11 of human MAX (NP_002373.3). |
Sequence: | VESD E |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | bHLHd4; Phospho-MAX-S11 |
Positive Sample: | Jurkat |
Conjugate: | Unconjugated |
Cellular Localization: | Cell projection, Nucleus, dendrite. |
Calculated MW: | 18kDa |
Observed MW: | 21kDa |
The protein encoded by this gene is a member of the basic helix-loop-helix leucine zipper (bHLHZ) family of transcription factors. It is able to form homodimers and heterodimers with other family members, which include Mad, Mxi1 and Myc. Myc is an oncoprotein implicated in cell proliferation, differentiation and apoptosis. The homodimers and heterodimers compete for a common DNA target site (the E box) and rearrangement among these dimer forms provides a complex system of transcriptional regulation. Mutations of this gene have been reported to be associated with hereditary pheochromocytoma. A pseudogene of this gene is located on the long arm of chromosome 7. Alternative splicing results in multiple transcript variants.
Purification Method: | Affinity purification |
Gene ID: | 4149 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |