The JTB Polyclonal Antibody (CAB10427) is a valuable tool for researchers studying the JTB protein, a member of the Jumonji family of histone demethylases involved in epigenetic regulation. This antibody, generated in rabbits, has high reactivity with human samples and is validated for use in Western blot applications. By binding to the JTB protein, this antibody enables researchers to detect and analyze JTB expression in various cell types, making it an essential tool for studies in epigenetics and cancer research.
JTB, also known as Jumping translocation breakpoint protein, plays a critical role in chromatin remodeling and gene expression regulation. Its involvement in epigenetic processes makes it a promising target for research into cancer development, progression, and treatment. By understanding the function of JTB, researchers can uncover new insights into the mechanisms underlying cancer and potentially identify novel therapeutic targets for intervention.
Product Name:
JTB Rabbit Polyclonal Antibody
SKU:
CAB10427
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 31-105 of human JTB (NP_006685.1).
Cytoplasm, Membrane, Mitochondrion, Single-pass type I membrane protein, centrosome, cytoskeleton, microtubule organizing center, spindle.
Calculated MW:
16kDa
Observed MW:
16kDa
Enables protein kinase binding activity. Involved in mitotic cytokinesis and positive regulation of protein kinase activity. Located in cytoplasm and midbody. Colocalizes with centrosome and spindle.
Purification Method:
Affinity purification
Gene ID:
10899
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using JTB antibody (CAB10427) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 60s.
