The C8orf4 Polyclonal Antibody (CAB6241) is a valuable tool for researchers studying the C8orf4 protein, a gene with potential implications in various biological processes. This antibody, generated in rabbits, exhibits high reactivity with human samples and is validated for use in Western blot applications. It specifically targets the C8orf4 protein, allowing for accurate detection and analysis in a variety of cell types, making it an ideal choice for investigations in molecular biology and genetics.
C8orf4 is a relatively understudied gene with limited information available regarding its functions and role in cellular processes. Research on this protein could provide insights into its involvement in cell signaling pathways, protein interactions, or disease mechanisms. By using the C8orf4 Polyclonal Antibody, researchers can explore the potential functions and regulatory mechanisms of this gene, opening up new avenues for understanding its biological significance.
Product Name:
C8orf4 Rabbit Polyclonal Antibody
SKU:
CAB6241
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-106 of human C8orf4 (NP_064515.1).
This gene encodes a small, monomeric, predominantly unstructured protein that functions as a positive regulator of the Wnt/beta-catenin signaling pathway. This protein interacts with a repressor of beta-catenin mediated transcription at nuclear speckles. It is thought to competitively block interactions of the repressor with beta-catenin, resulting in up-regulation of beta-catenin target genes. The encoded protein may also play a role in the NF-kappaB and ERK1/2 signaling pathways. Expression of this gene may play a role in the proliferation of several types of cancer including thyroid cancer, breast cancer and hematological malignancies.
Purification Method:
Affinity purification
Gene ID:
56892
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of lysates from Rat kidney, using C8orf4 Rabbit pAb (CAB6241) at 1:7000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 180s.
