The BTG1 Polyclonal Antibody (CAB6359) is a valuable tool for researchers studying BTG1, a protein involved in cell growth and differentiation. This antibody, generated in rabbits, exhibits high specificity and sensitivity when used with human samples, making it suitable for Western blot applications. By binding to the BTG1 protein, this antibody allows for the detection and analysis of BTG1 expression in various cell types, making it ideal for investigations in cell biology and cancer research.
BTG1, a member of the BTG/Tob family of proteins, plays a crucial role in regulating cell cycle progression and proliferation. Its function in controlling cellular growth and differentiation makes it a key target for studies on cancer development and other pathological conditions. By understanding the mechanisms underlying BTG1 activity, researchers can gain insights into potential therapeutic strategies for treating cancer and other diseases where cellular proliferation is dysregulated.
Product Name:
BTG1 Rabbit Polyclonal Antibody
SKU:
CAB6359
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 22-171 of human BTG1 (NP_001722.1).
This gene is a member of an anti-proliferative gene family that regulates cell growth and differentiation. Expression of this gene is highest in the G0/G1 phases of the cell cycle and downregulated when cells progressed through G1. The encoded protein interacts with several nuclear receptors, and functions as a coactivator of cell differentiation. This locus has been shown to be involved in a t(8;12)(q24;q22) chromosomal translocation in a case of B-cell chronic lymphocytic leukemia.
Purification Method:
Affinity purification
Gene ID:
694
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Immunofluorescence analysis of U2OS cells using BTG1 antibody (CAB6359).
