The Protein 4.1 Polyclonal Antibody (CAB2490) is a vital tool for researchers studying Protein 4.1, a key protein involved in maintaining cell shape and function. This antibody, produced in rabbits, is highly specific to human samples and is validated for use in Western blot applications. It specifically binds to Protein 4.1, allowing for precise detection and analysis in a variety of cell types, making it an essential tool for studies in cell biology, hematology, and cancer research.
Protein 4.1 is a critical component of the cytoskeleton, playing a crucial role in cell membrane stability and organization. Dysregulation of Protein 4.1 has been implicated in various diseases, including hereditary spherocytosis and certain types of cancers. By investigating the function and expression of Protein 4.1 using this antibody, researchers can gain insights into the mechanisms underlying these conditions and potentially identify new therapeutic targets for intervention.
Product Name:
EPB41 Rabbit Polyclonal Antibody
SKU:
CAB2490
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 210-500 of human EPB41 (NP_001159478.1).
The protein encoded by this gene, together with spectrin and actin, constitute the red cell membrane cytoskeletal network. This complex plays a critical role in erythrocyte shape and deformability. Mutations in this gene are associated with type 1 elliptocytosis (EL1). Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Purification Method:
Affinity purification
Gene ID:
2035
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates, using EPB41 Rabbit pAb (CAB2490) at 1:700 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
