The Prorelaxin H2 Polyclonal Antibody (CAB6969) is a valuable tool for researchers studying Prorelaxin H2, a hormone involved in reproductive health and cardiovascular function. This antibody, produced and validated in rabbits, specifically targets Prorelaxin H2 and is highly reactive with human samples, making it ideal for use in various research applications, including Western blotting.Prorelaxin H2 is known for its role in promoting vasodilation and relaxation of smooth muscle, making it a key player in reproductive processes and cardiovascular health.
Studies have also suggested its potential therapeutic benefits in treating conditions such as hypertension and congestive heart failure. The Prorelaxin H2 Polyclonal Antibody enables researchers to detect and analyze Prorelaxin H2 expression in different cell types, providing valuable insights into its function and potential applications in disease research and drug development.
Product Name:
RLN2 Rabbit Polyclonal Antibody
SKU:
CAB6969
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 25-185 of human RLN2 (NP_604390.1).
This gene encodes a member of the relaxin subfamily and insulin superfamily of peptide hormones. In humans there are three non-allelic relaxin genes. This gene encodes multiple protein isoforms, at least one of which undergoes proteolytic processing. This processing generates relaxin A and B chains that are linked by disulfide bonds to form the mature peptide hormone. This hormone plays a role in the male and female reproductive systems and was initially noted for its role in pregnancy. This protein also plays broader roles in the cardiovascular system, including in the regulation of blood pressure and control of heart rate, and data from animal models shows that this protein may have anti-fibrotic and cardioprotective effects.
Purification Method:
Affinity purification
Gene ID:
6019
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of lysates from 22Rv1 cells, using RLN2 Rabbit pAb (CAB6969) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
