The Promotilin Polyclonal Antibody (CAB6388) is a valuable tool for research involving Promotilin, a peptide hormone that plays a crucial role in the regulation of gastrointestinal motility. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in a variety of applications, including Western blot analysis. By specifically binding to Promotilin, this antibody enables accurate detection and analysis in various cell types, making it an ideal choice for studies in gastroenterology and digestive health research.Promotilin is known for its stimulatory effect on gastrointestinal motility, making it a key player in the regulation of digestion and nutrient absorption.
Dysregulation of Promotilin has been implicated in various gastrointestinal disorders, highlighting its importance as a potential therapeutic target. Research into the function and activity of Promotilin is essential for developing strategies to manage conditions such as gastroparesis, irritable bowel syndrome, and other motility disorders. The Promotilin Polyclonal Antibody provides a valuable tool for investigating the role of Promotilin in these contexts, paving the way for the development of novel treatment approaches.
Product Name:
MLN Rabbit Polyclonal Antibody
SKU:
CAB6388
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 26-115 of human MLN (NP_002409.1).
This gene encodes a small peptide hormone that is secreted by cells of the small intestine to regulate gastrointestinal contractions and motility. Proteolytic processing of the secreted protein produces the mature peptide and a byproduct referred to as motilin-associated peptide (MAP). Three transcript variants encoding different preproprotein isoforms but the same mature peptide have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
4295
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using MLN Rabbit pAb (CAB6388) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
