The Prolactin Polyclonal Antibody (CAB1618) is a valuable tool for researchers studying prolactin, a hormone known for its role in lactation and reproduction. This antibody, produced in rabbits, is highly specific to human samples and has been validated for use in Western blot applications. It enables the detection and analysis of prolactin protein in various tissues and cell types, making it ideal for studies related to endocrinology, fertility, and breast cancer research.Prolactin is a versatile hormone with diverse functions beyond lactation, including immune regulation, metabolism, and behavior.
Dysregulation of prolactin levels has been linked to various disorders such as infertility, polycystic ovary syndrome, and breast cancer. By studying the expression and activity of prolactin using this antibody, researchers can gain insights into the mechanisms underlying these conditions and potentially identify new therapeutic targets for treatment.
Product Name:
PRL Rabbit Polyclonal Antibody
SKU:
CAB1618
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 29-227 of human PRL (NP_001157030.1).
This gene encodes the anterior pituitary hormone prolactin. This secreted hormone is a growth regulator for many tissues, including cells of the immune system. It may also play a role in cell survival by suppressing apoptosis, and it is essential for lactation. Alternative splicing results in multiple transcript variants that encode the same protein.
Purification Method:
Affinity purification
Gene ID:
5617
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of extracts of normal 293F cells and 293F transfected with 293F-Prolactin-Avi-His-C protein, using PRL Rabbit pAb (CAB1618) at 1:700 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 5s.
