PROKR1 Antibody (PACO29184)
- SKU:
- PACO29184
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
PROKR1 Antibody (PACO29184)
The ProKR1 Polyclonal Antibody (PAC029184) is a valuable tool for researchers studying Prokineticin receptor 1 (ProKR1), a G protein-coupled receptor involved in various physiological processes including inflammation, pain perception, and development of the nervous system. This antibody, raised in rabbits, is highly specific for human samples and has been validated for use in Western blot applications.ProKR1 is known for its role in modulating immune responses and has been linked to various inflammatory disorders and cancer progression. By targeting ProKR1 with this antibody, researchers can detect and analyze ProKR1 expression in different cell types, providing valuable insights into its function and potential as a therapeutic target in diseases such as cancer, autoimmune disorders, and chronic inflammatory conditions.
Understanding the mechanisms underlying ProKR1 signaling is essential for developing targeted therapies that can modulate immune responses and potentially alleviate symptoms of inflammation-related diseases. The ProKR1 Polyclonal Antibody offers a reliable tool for investigating ProKR1 function and is a valuable asset for researchers in the fields of immunology and cancer research.
| Antibody Name: | PROKR1 Antibody (PACO29184) |
| Antibody SKU: | PACO29184 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:20-1:200 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human Prokineticin receptor 1 protein (1-62AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Immunohistochemistry of paraffin-embedded human gastric cancer using PACO29184 at dilution of 1:100. |
| Background: | Receptor for prokineticin 1. Exclusively coupled to the G(q) subclass of heteromeric G proteins. Activation leads to mobilization of calcium, stimulation of phosphoinositide turnover and activation of p44/p42 mitogen-activated protein kinase. May play a role during early pregnancy. |
| Synonyms: | Prokineticin receptor 1 (PK-R1) (G-protein coupled receptor 73) (G-protein coupled receptor ZAQ) (GPR73a), PROKR1, GPR73 PKR1 |
| UniProt Protein Function: | PROKR1: Receptor for prokineticin 1. Exclusively coupled to the G(q) subclass of heteromeric G proteins. Activation leads to mobilization of calcium, stimulation of phosphoinositide turnover and activation of p44/p42 mitogen-activated protein kinase. Belongs to the G-protein coupled receptor 1 family. |
| UniProt Protein Details: | Protein type:Receptor, GPCR; Membrane protein, integral; Membrane protein, multi-pass; GPCR, family 1 Chromosomal Location of Human Ortholog: 2p13.1 Cellular Component: integral to plasma membrane; plasma membrane Molecular Function:G-protein coupled receptor activity; neuropeptide Y receptor activity Biological Process: cell surface receptor linked signal transduction; circadian rhythm; G-protein coupled receptor protein signaling pathway; negative regulation of apoptosis; neuropeptide signaling pathway |
| UniProt Code: | Q8TCW9 |
| NCBI GenInfo Identifier: | 33112428 |
| NCBI Gene ID: | 10887 |
| NCBI Accession: | Q8TCW9.1 |
| UniProt Secondary Accession: | Q8TCW9,Q53QT9, Q8NFJ7, A5JUU2, |
| UniProt Related Accession: | Q8TCW9 |
| Molecular Weight: | 44,770 Da |
| NCBI Full Name: | Prokineticin receptor 1 |
| NCBI Synonym Full Names: | prokineticin receptor 1 |
| NCBI Official Symbol: | PROKR1Â Â |
| NCBI Official Synonym Symbols: | ZAQ; PKR1; GPR73; GPR73a  |
| NCBI Protein Information: | prokineticin receptor 1 |
| UniProt Protein Name: | Prokineticin receptor 1 |
| UniProt Synonym Protein Names: | G-protein coupled receptor 73; G-protein coupled receptor ZAQ; GPR73a |
| Protein Family: | Prokineticin receptor |
| UniProt Gene Name: | PROKR1Â Â |
| UniProt Entry Name: | PKR1_HUMAN |
| Antibodies | ELISA Kits |
| PROKR1 Antibody (PACO06765) | Human PKR1 (Prokineticin Receptor 1) CLIA Kit (HUES01014) |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |
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PROKR1 Antibody (PACO06765)
