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PROK1 Rabbit Monoclonal Antibody (CAB19268)

SKU:
CAB19268
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
€139 - €419
Frequently bought together:

Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:PROK1 Rabbit Monoclonal Antibody
SKU:CAB19268
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human,Mouse,Rat
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-105 of human PROK1 (P58294).
Sequence:MRGA TRVS IMLL LVTV SDCA VITG ACER DVQC GAGT CCAI SLWL RGLR MCTP LGRE GEEC HPGS HKVP FFRK RKHH TCPC LPNL LCSR FPDG RYRC SMDL KNIN F
Tested Applications:WB IF/ICC ELISA
Recommended Dilution:WB,1:500 - 1:1000 IF/ICC,1:50 - 1:200
Synonyms:PK1; PRK1; EGVEGF; PROK1
Positive Sample:293T,HepG2,Mouse liver,Mouse kidney,Rat ovary,Rat kidney
Conjugate:Unmodified
Cellular Localization:extracellular region
Calculated MW:12kDa
Observed MW:14kDa

The protein encoded by this gene induces proliferation, migration, and fenestration (the formation of membrane discontinuities) in capillary endothelial cells derived from endocrine glands. It has little or no effect on a variety of other endothelial and non-endothelial cell types. Its expression is restricted to the steroidogenic glands (ovary, testis, adrenal, and placenta), is induced by hypoxia, and often complementary to the expression of vascular endothelial growth factor (VEGF), suggesting that these molecules function in a coordinated manner.

Purification Method:Affinity purification
Gene ID:84432
Clone Number:ARC2439
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Product ImageWestern blot analysis of extracts of various cell lines, using PROK1 antibody (CAB19268) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 180s.

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