The Prohibitin Rabbit Monoclonal Antibody (CAB19530) is a valuable tool for research involving prohibitin, a protein known for its role in various cellular processes, including cell cycle regulation, apoptosis, and mitochondrial function. The antibody, generated in rabbits, demonstrates high specificity and sensitivity in detecting prohibitin in human samples and is verified for use in applications such as immunofluorescence and immunohistochemistry.Prohibitin, a highly conserved and multifunctional protein, is implicated in diverse cellular functions, making it a target of interest in studies related to cancer, aging, and metabolic disorders.
Its involvement in regulating cell proliferation and survival highlights its potential as a therapeutic target for conditions characterized by dysregulated cell growth.By utilizing the Prohibitin Rabbit Monoclonal Antibody (CAB19530), researchers can gain valuable insights into the biological functions of prohibitin and its implications in disease pathogenesis. This antibody offers a reliable and effective means of detecting and analyzing prohibitin expression in various experimental settings, providing a deeper understanding of its mechanisms and potential applications in clinical research.
Product Name:
Prohibitin Rabbit Monoclonal Antibody
SKU:
CAB19530
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 100-200 of human Prohibitin (P35232).
Sequence:
ASQL PRIF TSIG EDYD ERVL PSIT TEIL KSVV ARFD AGEL ITQR ELVS RQVS DDLT ERAA TFGL ILDD VSLT HLTF GKEF TEAV EAKQ VAQQ EAER ARFV V
This gene is evolutionarily conserved, and its product is proposed to play a role in human cellular senescence and tumor suppression. Antiproliferative activity is reported to be localized to the 3' UTR, which is proposed to function as a trans-acting regulatory RNA. Several pseudogenes of this gene have been identified. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
5245
Clone Number:
ARC0007
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using Prohibitin antibody (CAB19530) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 5s.
