The Prohibitin Polyclonal Antibody (CAB0056) is a valuable tool for researchers studying prohibitin, a multifunctional protein that plays a role in various cellular processes, including cell cycle regulation, apoptosis, and mitochondrial function. This antibody, generated in rabbits, has been validated for use in Western blot applications and is highly specific for detecting prohibitin in human samples.Prohibitin is known to be involved in the maintenance of mitochondrial function and has been implicated in diseases such as cancer and neurodegenerative disorders.
By targeting prohibitin, researchers can gain insights into the molecular mechanisms underlying these diseases and explore potential therapeutic interventions.With its high reactivity and specificity, the Prohibitin Polyclonal Antibody is a valuable tool for researchers in the fields of cell biology, cancer research, and neurology. Its ability to detect prohibitin in various cell types makes it ideal for investigating the role of this protein in disease pathology and potential therapeutic targets.
Product Name:
Prohibitin Rabbit Polyclonal Antibody
SKU:
CAB0056
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 73-272 of human Prohibitin (NP_002625.1).
This gene is evolutionarily conserved, and its product is proposed to play a role in human cellular senescence and tumor suppression. Antiproliferative activity is reported to be localized to the 3' UTR, which is proposed to function as a trans-acting regulatory RNA. Several pseudogenes of this gene have been identified. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
5245
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of various lysates using Prohibitin Rabbit pAb (CAB0056) at 1:500 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
