The Progonadoliberin-1 Polyclonal Antibody (CAB5625) is a critical tool for researchers studying the Progonadoliberin-1 protein, which is involved in the regulation of reproduction and sexual development. This antibody, produced in rabbits, is highly specific to human samples and has been validated for use in immunohistochemistry and ELISA applications. By binding to Progonadoliberin-1, researchers can accurately detect and analyze the protein in various tissues and cell types, making it an essential component for studies in reproductive biology and hormone regulation.Progonadoliberin-1, also known as luteinizing hormone-releasing hormone, plays a pivotal role in stimulating the release of reproductive hormones from the pituitary gland, which in turn regulates the menstrual cycle, ovulation, and fertility.
Understanding the function and expression of Progonadoliberin-1 is crucial for investigations into infertility, hormonal disorders, and reproductive health. By utilizing the Progonadoliberin-1 Polyclonal Antibody, researchers can gain valuable insights into the role of this protein in reproductive physiology and potentially develop new therapies for reproductive disorders.
Product Name:
GNRH1 Rabbit Polyclonal Antibody
SKU:
CAB5625
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 24-92 of human GNRH1 (NP_001076580.1).
This gene encodes a preproprotein that is proteolytically processed to generate a peptide that is a member of the gonadotropin-releasing hormone (GnRH) family of peptides. Alternative splicing results in multiple transcript variants, at least one of which is secreted and then cleaved to generate gonadoliberin-1 and GnRH-associated peptide 1. Gonadoliberin-1 stimulates the release of luteinizing and follicle stimulating hormones, which are important for reproduction. Mutations in this gene are associated with hypogonadotropic hypogonadism.
Purification Method:
Affinity purification
Gene ID:
2796
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of extracts of Mouse lung, using GNRH1 antibody (CAB5625) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 180s.
