The Progesterone Receptor Rabbit Monoclonal Antibody (CAB19697) is a cutting-edge tool for researchers studying the progesterone receptor, a key regulator of hormone signaling pathways. This antibody, derived from rabbit monoclonal cells, exhibits high specificity and sensitivity towards human samples, making it an ideal choice for Western blot applications.The progesterone receptor is a pivotal player in various physiological processes, including reproduction, mammary gland development, and immune regulation. Dysregulation of this receptor has been implicated in numerous diseases, such as breast cancer and endometrial cancer.
By targeting the progesterone receptor, researchers can gain valuable insights into the molecular mechanisms underlying these pathologies and potentially identify novel therapeutic strategies.With its advanced technology and reliable performance, the Progesterone Receptor Rabbit Monoclonal Antibody (CAB19697) offers a valuable tool for investigating the role of the progesterone receptor in health and disease. Whether studying hormone signaling pathways, cancer biology, or reproductive disorders, this antibody is essential for unlocking the mysteries of progesterone receptor function.
Product Name:
Progesterone Receptor Rabbit Monoclonal Antibody
SKU:
CAB19697
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 260-330 of human Progesterone Receptor (NP_000917.3).
This gene encodes a member of the steroid receptor superfamily. The encoded protein mediates the physiological effects of progesterone, which plays a central role in reproductive events associated with the establishment and maintenance of pregnancy. This gene uses two distinct promotors and translation start sites in the first exon to produce several transcript variants, both protein coding and non-protein coding. Two of the isoforms (A and B) are identical except for an additional 165 amino acids found in the N-terminus of isoform B and mediate their own response genes and physiologic effects with little overlap.
Purification Method:
Affinity purification
Gene ID:
5241
Clone Number:
ARC51400
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of extracts of BT-474 cells, using Progesterone Receptor antibody (CAB19697) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 3min.
