The Progesterone Receptor Monoclonal Antibody (CAB22061) is a valuable tool for researchers studying the progesterone receptor, a critical hormone receptor involved in various physiological processes. This monoclonal antibody, specifically designed for human samples, is highly sensitive and specific for detecting the progesterone receptor in Western blot applications.The progesterone receptor plays a key role in regulating the effects of progesterone, a hormone involved in reproductive functions, pregnancy, and other biological processes. Dysregulation of the progesterone receptor has been linked to conditions such as infertility, endometrial cancer, and breast cancer, making it a key target for research and therapeutic development.
By using the Progesterone Receptor Monoclonal Antibody (CAB22061), researchers can accurately detect and analyze progesterone receptor expression in various cell types, shedding light on its role in normal physiology and disease states. This antibody is a valuable tool for studies in reproductive biology, oncology, and hormone-related disorders, providing crucial insights for developing targeted therapies and diagnostics.
Product Name:
Progesterone Receptor Monoclonal Antibody
SKU:
CAB22061
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant protein of human Progesterone Receptor.
This gene encodes a member of the steroid receptor superfamily. The encoded protein mediates the physiological effects of progesterone, which plays a central role in reproductive events associated with the establishment and maintenance of pregnancy. This gene uses two distinct promotors and translation start sites in the first exon to produce several transcript variants, both protein coding and non-protein coding. Two of the isoforms (A and B) are identical except for an additional 165 amino acids found in the N-terminus of isoform B and mediate their own response genes and physiologic effects with little overlap.
Purification Method:
Affinity purification
Gene ID:
5241
Clone Number:
ARC5121-01
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of lysates from T-47D cells, using Progesterone Receptor Rabbit mAb (CAB22061) at 1:2000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 4s.
