Similarly, the Profilin1 Rabbit Monoclonal Antibody (CAB9188) is a powerful tool for researchers studying Profilin1, a key protein involved in regulating actin polymerization and cytoskeletal dynamics. This antibody, generated in rabbits, offers high specificity and sensitivity when detecting Profilin1 in human samples, making it an essential reagent for studies in cell biology and cancer research.Profilin1 is known for its role in cell migration, division, and shape changes, making it a critical player in processes like cell motility and tumor metastasis.
By targeting Profilin1 with this antibody, researchers can gain valuable insights into the molecular mechanisms underlying these cellular functions, leading to potential therapeutic targets for diseases such as cancer and neurodegenerative disorders.Overall, the Profilin1 Rabbit Monoclonal Antibody (CAB9188) is a reliable tool for elucidating the functions of Profilin1 in various cellular processes, offering new avenues for understanding and potentially treating diseases associated with dysregulation of this important protein.
Product Name:
Profilin1 Rabbit Monoclonal Antibody
SKU:
CAB9188
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 61-140 of human PFN1 (P07737).
This gene encodes a member of the profilin family of small actin-binding proteins. The encoded protein plays an important role in actin dynamics by regulating actin polymerization in response to extracellular signals. Deletion of this gene is associated with Miller-Dieker syndrome, and the encoded protein may also play a role in Huntington disease. Multiple pseudogenes of this gene are located on chromosome 1.
Purification Method:
Affinity purification
Gene ID:
5216
Clone Number:
ARC1469
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using Profilin1 Rabbit mAb (CAB9188) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
