The Profilin-2 Polyclonal Antibody (CAB3074) is a valuable tool for researchers studying Profilin-2, a key protein involved in actin polymerization and cytoskeleton dynamics. This antibody, generated in rabbits, is highly specific to human Profilin-2 and is validated for use in various applications, including Western blot and immunofluorescence.Profilin-2 is essential for cell motility, cell division, and intracellular trafficking, making it pivotal in cellular processes like cell migration and adhesion. Dysregulation of Profilin-2 has been linked to various diseases, including cancer and neurodegenerative disorders, making it a potential target for therapeutic interventions.
By utilizing the Profilin-2 Polyclonal Antibody (CAB3074), researchers can accurately detect and analyze Profilin-2 expression in different cell types and tissues, advancing our understanding of its role in health and disease. This antibody is a valuable asset for studies in cell biology, cancer research, and neurology, providing crucial insights into the functions of Profilin-2 in various physiological and pathological conditions.
Product Name:
PFN2 Rabbit Polyclonal Antibody
SKU:
CAB3074
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 100-140 of human PFN2 (P35080).
Sequence:
NVAV GRAG RVLV FVMG KEGV HGGG LNKK AYSM AKYL RDSG F
The protein encoded by this gene is a ubiquitous actin monomer-binding protein belonging to the profilin family. It is thought to regulate actin polymerization in response to extracellular signals. There are two alternatively spliced transcript variants encoding different isoforms described for this gene.
Purification Method:
Affinity purification
Gene ID:
5217
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using PFN2 antibody (CAB3074) at 1:500 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 90s.
