The Profilin-1 Polyclonal Antibody (CAB1164) is a valuable tool for researchers studying the functions of Profilin-1, a key protein involved in actin polymerization and regulation of the cytoskeleton. This antibody, raised in rabbits, is highly specific and reacts strongly with human samples, making it ideal for use in Western blot applications. By binding to Profilin-1, this antibody enables accurate detection and analysis of the protein in various cell types, facilitating investigations into cell motility, cell shape, and cell division.Profilin-1 plays a crucial role in regulating actin dynamics, which are essential for processes such as cell migration, cell adhesion, and intracellular transport.
Dysregulation of Profilin-1 has been implicated in various diseases, including cancer, neurological disorders, and autoimmune conditions. Therefore, understanding the functions of Profilin-1 is essential for elucidating disease mechanisms and developing targeted therapies.Overall, the Profilin-1 Polyclonal Antibody (CAB1164) is a reliable tool for researchers interested in studying the role of Profilin-1 in cellular processes and disease pathogenesis. Its high specificity and sensitivity make it a valuable asset in immunology, cancer research, and cell biology studies.
Product Name:
Profilin1 Rabbit Polyclonal Antibody
SKU:
CAB1164
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat,Monkey
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-140 of human Profilin1 (NP_005013.1).
This gene encodes a member of the profilin family of small actin-binding proteins. The encoded protein plays an important role in actin dynamics by regulating actin polymerization in response to extracellular signals. Deletion of this gene is associated with Miller-Dieker syndrome, and the encoded protein may also play a role in Huntington disease. Multiple pseudogenes of this gene are located on chromosome 1.
Purification Method:
Affinity purification
Gene ID:
5216
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using Profilin1 Polyclonal Antibody (CAB1164) at 1:500 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
