The ProCR Polyclonal Antibody (CAB5763) is specifically designed for research involving ProCR, a protein involved in regulating immune responses and inflammatory processes. This antibody, produced in rabbits, is highly reactive with human samples and has been validated for use in Western blot applications. By binding to the ProCR protein, this antibody enables researchers to detect and analyze ProCR expression in various cell types, making it a valuable tool for studies in immunology and cancer research.ProCR, also known as a key regulator of inflammation, plays a crucial role in modulating immune responses and maintaining immune homeostasis.
Its involvement in inflammatory pathways makes it an important target for research into diseases such as cancer, autoimmune disorders, and chronic inflammatory conditions. Understanding the function of ProCR is essential for developing novel therapies that target or modulate immune responses in the context of these diseases.In summary, the ProCR Polyclonal Antibody (CAB5763) offers researchers a reliable tool for studying the role of ProCR in immune regulation and inflammatory processes, providing valuable insights for the development of novel therapeutic strategies in various disease settings.
Product Name:
PROCR Rabbit Polyclonal Antibody
SKU:
CAB5763
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 18-210 of human PROCR (NP_006395.2).
The protein encoded by this gene is a receptor for activated protein C, a serine protease activated by and involved in the blood coagulation pathway. The encoded protein is an N-glycosylated type I membrane protein that enhances the activation of protein C. Mutations in this gene have been associated with venous thromboembolism and myocardial infarction, as well as with late fetal loss during pregnancy. The encoded protein may also play a role in malarial infection and has been associated with cancer.
Purification Method:
Affinity purification
Gene ID:
10544
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using PROCR antibody (CAB5763) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
