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Pro-MMP9 Monoclonal Antibody

SKU:
CAB23919
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Mouse
Host Species:
Rabbit
Isotype:
IgG
Applications:
WB
$167 - $635
Frequently bought together:

Description

Pro-MMP9 Monoclonal Antibody (CAB23919)

The Pro-MMP9 Monoclonal Antibody from Assay Genie is a highly specific and sensitive tool for studying matrix metalloproteinase 9 (MMP9), a key enzyme involved in extracellular matrix remodeling and tissue repair. This monoclonal antibody, developed using state-of-the-art technology, recognizes human MMP9 with exceptional accuracy and precision, making it an essential component of research in cancer biology, inflammation, and wound healing.MMP9, also known as gelatinase B, is a critical player in the degradation of extracellular matrix proteins and basement membrane components, essential processes for tissue remodeling and cell migration. Dysregulation of MMP9 activity has been implicated in numerous pathological conditions, including cancer metastasis, arthritis, and cardiovascular diseases.

By targeting MMP9 with this highly specific antibody, researchers can gain valuable insights into its role in disease progression and potential therapeutic interventions.The Pro-MMP9 Monoclonal Antibody is validated for use in a variety of experimental applications, including Western blotting, immunofluorescence, and immunohistochemistry. Its high sensitivity and specificity ensure accurate detection and quantification of MMP9 protein levels in cell lysates, tissue samples, and culture supernatants. With its exceptional performance and reliability, this antibody is a valuable tool for scientists investigating the molecular mechanisms underlying disease progression and potential targets for therapeutic intervention.

Product Name:Pro-MMP9 Monoclonal Antibody
Product Code:CAB23919
Reactivity:Mouse
Applications:Western blotting
Host Species:Rabbit
Purification Method:Affinity purification
Isotype:IgG
Clone No:ARC62081
Reactivity:Mouse
Tested Applications:WB, ELISA
Key Applications:Western blotting
Recommended Dilution:WB 1:500-1:1000
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3.
Positive Samples:Mouse Pro-MMP9 protein
Cellular Location:Secreted, Extracellular space, Extracellular matrix.

This gene encodes a member of the matrix metalloproteinase family of extracellular matrix-degrading enzymes that are involved in tissue remodeling, wound repair, progression of atherosclerosis and tumor invasion. The encoded preproprotein undergoes proteolytic processing to generate a mature, zinc-dependent endopeptidase enzyme that degrades collagens of type IV, V and XI, and elastin. Mice lacking the encoded protein exhibit an abnormal pattern of skeletal growth plate vascularization and ossification, reduced keratinocyte hyperproliferation at all neoplastic stages, a decreased incidence of invasive tumors, and resistance to experimental autoimmune encephalomyelitis.

Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 20-107 of mouse MMP9(NP_038627.1).
Sequence:APYQR QPTFV VFPKD LKTSN LTDTQ LAEAY LYRYG YTRAA QMMGE KQSLR PALLM LQKQL SLPQT GELDS QTLKA IRTPR CGVPD VGR
Synonyms:Clg4b, Gel B, MMP-9, B/MMP9, pro-MMP-9
Calculated MW:80KDa
Observed MW:40kDa

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