The PRMT7 Polyclonal Antibody (CAB17164) is an essential tool for researchers studying PRMT7, a key enzyme involved in protein arginine methylation and gene regulation. This rabbit polyclonal antibody is highly specific to PRMT7 and has been validated for its use in various applications, including Western blotting. With its ability to detect and analyze PRMT7 in different cell types, this antibody is perfect for studies in molecular biology, epigenetics, and cancer research.PRMT7 plays a crucial role in numerous cellular processes, including DNA damage repair, RNA splicing, and cell signaling pathways.
Dysregulation of PRMT7 has been linked to various diseases, such as cancer, neurological disorders, and metabolic conditions, making it a compelling target for therapeutic interventions. By understanding the function of PRMT7, researchers can develop novel treatments that target this enzyme and its associated pathways, paving the way for new advancements in personalized medicine and drug development.
Product Name:
PRMT7 Rabbit Polyclonal Antibody
SKU:
CAB17164
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 513-692 of human PRMT7 (NP_061896.1).
This gene encodes a member of the protein arginine N-methyltransferase family of proteins. The encoded enzyme transfers single methyl groups to arginine residues to generate monomethylarginines on histone proteins as well as other protein substrates. This enzyme plays a role in a wide range of biological processes, including neuronal differentiation, male germ line imprinting, small nuclear ribonucleoprotein biogenesis, and regulation of the Wnt signaling pathway. Mutations in this gene underlie multiple related syndromes in human patients characterized by intellectual disability, short stature and other features. The encoded protein may promote breast cancer cell invasion and metastasis in human patients.
Purification Method:
Affinity purification
Gene ID:
54496
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Immunohistochemistry analysis of paraffin-embedded human breast cancer using PRMT7 Rabbit pAb (CAB17164) at dilution of 1:200 (40x lens).Perform microwave antigen retrieval with 10 mM PBS buffer pH 7.2 before commencing with IHC staining protocol.
