The PRMT3 Polyclonal Antibody (CAB13068) is a valuable tool for researchers studying PRMT3, a protein involved in the regulation of various cellular processes including gene expression, protein function, and signaling pathways. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications.PRMT3, also known as Protein Arginine Methyltransferase 3, plays a crucial role in protein regulation through the addition of methyl groups to arginine residues. Dysregulation of PRMT3 has been linked to various diseases, making it a promising target for therapeutic interventions.
By using the PRMT3 Polyclonal Antibody, researchers can effectively detect and analyze PRMT3 protein levels in different cell types, providing valuable insights for studies in cell biology, molecular biology, and disease mechanisms.With its specificity and sensitivity in detecting PRMT3 protein, this antibody is an essential tool for investigating the function and significance of PRMT3 in cellular processes, offering potential implications for drug development and disease treatment strategies.
Product Name:
[KO Validated] PRMT3 Rabbit Polyclonal Antibody
SKU:
CAB13068
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-220 of human PRMT3 (NP_005779.1).
This gene belongs to the protein arginine methyltransferase (PRMT) family. The encoded enzyme catalyzes the methylation of guanidino nitrogens of arginyl residues of proteins. The enzyme acts on 40S ribosomal protein S2 (rpS2), which is its major in-vivo substrate, and is involved in the proper maturation of the 80S ribosome. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
10196
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from mouse brain, using [KO Validated] PRMT3 Rabbit pAb (CAB13068) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
