The PRMT2 Polyclonal Antibody (AB-1122) is a valuable tool for researchers studying PRMT2, a protein known for its role in regulating gene expression and cell growth. This antibody, produced in rabbits, specifically targets PRMT2 in human samples and is validated for use in Western blot applications. By binding to PRMT2, this antibody allows for the detection and analysis of PRMT2 levels in various cell types, making it an essential component for studies in molecular biology and cancer research.PRMT2 is a type II protein arginine methyltransferase that catalyzes the addition of methyl groups to arginine residues in histones and other proteins, influencing various cellular processes such as transcriptional regulation and DNA repair.
Dysregulation of PRMT2 activity has been implicated in diseases such as cancer and neurodegenerative disorders, highlighting the importance of studying its function. By utilizing the PRMT2 Polyclonal Antibody, researchers can further elucidate the role of PRMT2 in these pathological conditions and potentially identify novel therapeutic targets.
Product Name:
PRMT2 Polyclonal Antibody
SKU:
CAB21828
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 290-433 of human PRMT2 (NP_001526.2).
Enables several functions, including nuclear receptor binding activity; peroxisome proliferator activated receptor binding activity; and protein homodimerization activity. Involved in several processes, including histone methylation; regulation of androgen receptor signaling pathway; and regulation of transcription, DNA-templated. Located in cytosol and nucleoplasm.
Purification Method:
Affinity purification
Gene ID:
3275
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using PRMT2 antibody (CAB21828) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
