The PRMT2 Polyclonal Antibody (CAB5835) is a powerful tool for researchers studying PRMT2, a protein known for its role in various cellular processes including gene transcription and RNA processing. This antibody, produced in rabbits, is highly specific to human PRMT2 samples and has been validated for use in Western blot applications.PRMT2, a protein arginine methyltransferase, is involved in the post-translational modification of proteins through arginine methylation, impacting their function and activity. Research has suggested that PRMT2 plays a role in cell differentiation, proliferation, and signaling pathways, making it a key target for investigations in molecular and cellular biology.
By utilizing the PRMT2 Polyclonal Antibody, researchers can accurately detect and analyze PRMT2 expression in different cell types and tissues, aiding in the understanding of its functions and potential implications in diseases such as cancer, neurodegenerative disorders, and metabolic diseases. This antibody is a valuable tool for studies aiming to uncover the mechanisms underlying PRMT2 activity and its impact on cellular physiology.
Product Name:
[KO Validated] PRMT2 Rabbit Polyclonal Antibody
SKU:
CAB5835
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human PRMT2 (NP_996845.1).
Enables several functions, including nuclear receptor binding activity; peroxisome proliferator activated receptor binding activity; and protein homodimerization activity. Involved in several processes, including histone methylation; regulation of androgen receptor signaling pathway; and regulation of transcription, DNA-templated. Located in cytosol and nucleoplasm.
Purification Method:
Affinity purification
Gene ID:
3275
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of lysates from mouse lung, using [KO Validated] PRMT2 Rabbit pAb (CAB5835) at 1:1000 dilution._Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution._Lysates/proteins: 25μg per lane._Blocking buffer: 3% nonfat dry milk in TBST._Detection: ECL Enhanced Kit (AbGn00021)._Exposure time: 90s.