The PRMT1 Rabbit Monoclonal Antibody (CAB4502) is a valuable tool for researchers studying PRMT1, a key enzyme involved in the regulation of gene expression through protein arginine methylation. This antibody, generated in rabbits, exhibits high specificity and sensitivity in detecting PRMT1 in human samples, making it ideal for use in Western blot and immunohistochemistry applications.PRMT1 plays a crucial role in various cellular processes, including chromatin remodeling, RNA processing, and signal transduction, making it a target of interest in cancer research and other fields. The PRMT1 Rabbit Monoclonal Antibody enables accurate detection and analysis of PRMT1 expression levels in different cell types, providing valuable insights into its function and potential implications in disease.
By utilizing this antibody, researchers can further explore the role of PRMT1 in various biological pathways and potentially uncover new therapeutic targets for conditions related to gene regulation and protein modification. Studies using the PRMT1 Rabbit Monoclonal Antibody have the potential to advance our understanding of PRMT1 biology and its relevance in human health and disease.
Product Name:
PRMT1 Rabbit Monoclonal Antibody
SKU:
CAB4502
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human PRMT1 (Q99873).
This gene encodes a member of the protein arginine N-methyltransferase (PRMT) family. Post-translational modification of target proteins by PRMTs plays an important regulatory role in many biological processes, whereby PRMTs methylate arginine residues by transferring methyl groups from S-adenosyl-L-methionine to terminal guanidino nitrogen atoms. The encoded protein is a type I PRMT and is responsible for the majority of cellular arginine methylation activity. Increased expression of this gene may play a role in many types of cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 5.
Purification Method:
Affinity purification
Gene ID:
3276
Clone Number:
ARC1066
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates, using PRMT1 Rabbit mAb (CAB4502) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 3min.
