The PRKDC Polyclonal Antibody (CAB7716) is a powerful tool for researchers studying the PRKDC protein, which is involved in DNA repair and maintenance of genome stability. This antibody, produced in rabbits, has high specificity for human samples and is validated for use in Western blot applications. By targeting the PRKDC protein, this antibody allows for accurate detection and analysis in a variety of cell types, making it ideal for studies in genetics, oncology, and molecular biology.PRKDC, also known as DNA-dependent protein kinase catalytic subunit, plays a crucial role in responding to DNA damage and maintaining genomic integrity. Dysregulation of PRKDC has been implicated in various diseases, including cancer and genetic disorders.
By studying the function of PRKDC, researchers can gain insights into the mechanisms of DNA repair and potentially develop targeted therapies for diseases associated with genomic instability.Overall, the PRKDC Polyclonal Antibody is a valuable tool for investigating the role of PRKDC in DNA repair processes and its implications for disease development and progression. Its high reactivity and specificity make it a reliable choice for researchers looking to delve into the intricate mechanisms of genome maintenance and potential therapeutic targets.
Product Name:
PRKDC Rabbit Polyclonal Antibody
SKU:
CAB7716
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 3987-4086 of human DNA-PKcs (NP_008835.5).
This gene encodes the catalytic subunit of the DNA-dependent protein kinase (DNA-PK). It functions with the Ku70/Ku80 heterodimer protein in DNA double strand break repair and recombination. The protein encoded is a member of the PI3/PI4-kinase family.
Purification Method:
Affinity purification
Gene ID:
5591
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using DNA-PKcs Rabbit pAb (CAB7716) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
