The PRKD2 Polyclonal Antibody (CAB17670) is a valuable tool for researchers studying the protein kinase D2 (PRKD2) in various cellular processes. Designed for use in Western blot applications, this antibody is raised in rabbits and exhibits high reactivity with human samples. By binding specifically to PRKD2, this antibody enables precise detection and analysis of the protein in different cell types.PRKD2 is a key player in intracellular signaling pathways, regulating processes such as cell proliferation, differentiation, and apoptosis. Dysregulation of PRKD2 has been linked to various diseases, including cancer and cardiovascular disorders.
By studying the function and expression of PRKD2, researchers can gain insights into its role in disease development and progression.This PRKD2 Polyclonal Antibody is a valuable tool for investigating the role of PRKD2 in normal physiology and disease states. Its high specificity and sensitivity make it ideal for use in immunology and cancer research, providing researchers with a reliable means of studying PRKD2 in various experimental settings.
Product Name:
PRKD2 Rabbit Polyclonal Antibody
SKU:
CAB17670
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 450-550 of human PRKD2 (NP_057541.2).
The protein encoded by this gene belongs to the protein kinase D (PKD) family of serine/threonine protein kinases. This kinase can be activated by phorbol esters as well as by gastrin via the cholecystokinin B receptor (CCKBR) in gastric cancer cells. It can bind to diacylglycerol (DAG) in the trans-Golgi network (TGN) and may regulate basolateral membrane protein exit from TGN. Alternative splicing results in multiple transcript variants encoding different isoforms.
Purification Method:
Affinity purification
Gene ID:
25865
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using PRKD2 Rabbit pAb (CAB17670) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 3MIN.
