PRKCQ Rabbit Polyclonal Antibody (CAB5834)
- SKU:
- CAB5834
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Immunology
Description
Product Name: | PRKCQ Rabbit Polyclonal Antibody |
SKU: | CAB5834 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-230 of human PRKCQ (NP_006248.1). |
Sequence: | MSPF LRIG LSNF DCGS CQSC QGEA VNPY CAVL VKEY VESE NGQM YIQK KPTM YPPW DSTF DAHI NKGR VMQI IVKG KNVD LISE TTVE LYSL AERC RKNN GKTE IWLE LKPQ GRML MNAR YFLE MSDT KDMN EFET EGFF ALHQ RRGA IKQA KVHH VKCH EFTA TFFP QPTF CSVC HEFV WGLN KQGY QCRQ CNAA IHKK CIDK VIAK CTGS AINS RETM FHKE RFKI DM |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | PRKCT; nPKC-theta; PRKCQ |
Positive Sample: | HepG2,Rat testis |
Conjugate: | Unconjugated |
Cellular Localization: | Cell membrane, Cytoplasm, Peripheral membrane protein. |
Calculated MW: | 82kDa |
Observed MW: | 82kDa |
Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role. The protein encoded by this gene is one of the PKC family members. It is a calcium-independent and phospholipid-dependent protein kinase. This kinase is important for T-cell activation. It is required for the activation of the transcription factors NF-kappaB and AP-1, and may link the T cell receptor (TCR) signaling complex to the activation of the transcription factors.
Purification Method: | Affinity purification |
Gene ID: | 5588 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |