The PRKCDBP Polyclonal Antibody (CAB17247) is a valuable tool for researchers studying PRKCDBP, a protein involved in protein kinase C signaling pathways. This antibody, produced in rabbits, exhibits high specificity and sensitivity in detecting PRKCDBP in human samples, making it ideal for Western blot analysis. By targeting the PRKCDBP protein, researchers can gain insights into its function and involvement in various cellular processes.PRKCDBP, also known as protein kinase C delta-binding protein, plays a crucial role in mediating the downstream effects of protein kinase C activation, thereby regulating important cellular functions such as cell proliferation, differentiation, and apoptosis.
Its significance in signaling pathways makes it a promising target for studying diseases related to dysregulated protein kinase C signaling, such as cancer, cardiovascular disorders, and neurological diseases.By utilizing the PRKCDBP Polyclonal Antibody in their research, scientists can deepen their understanding of PRKCDBP's role in cellular signaling and explore its potential as a therapeutic target for diseases characterized by aberrant protein kinase C activity. This antibody is a valuable tool for advancing research in cell biology, oncology, and drug development.
Product Name:
PRKCDBP Rabbit Polyclonal Antibody
SKU:
CAB17247
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 75-160 of human PRKCDBP (NP_659477.2).
The protein encoded by this gene was identified as a binding protein of the protein kinase C, delta (PRKCD). The expression of this gene in cultured cell lines is strongly induced by serum starvation. The expression of this protein was found to be down-regulated in various cancer cell lines, suggesting the possible tumor suppressor function of this protein.
Purification Method:
Affinity purification
Gene ID:
112464
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from Rat heart, using PRKCDBP Rabbit pAb (CAB17247) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
