The PRKCA Monoclonal Antibody (CAB11107) is a vital tool for researchers studying the protein kinase C alpha (PRKCA) enzyme, which is involved in various cellular processes such as cell growth, differentiation, and apoptosis. This monoclonal antibody, produced using hybridoma technology, specifically targets PRKCA and is validated for use in applications such as immunofluorescence, immunohistochemistry, and flow cytometry.PRKCA is a key player in signaling pathways regulating cell proliferation and survival, making it a potential target for drug development in cancer and other diseases.
By utilizing the PRKCA Monoclonal Antibody, researchers can investigate the expression and localization of PRKCA in different cell types, leading to a better understanding of its role in health and disease.This antibody is a valuable tool for researchers in the fields of cell biology, cancer biology, and drug discovery, as it provides reliable detection and analysis of PRKCA in various experimental settings. Improve the quality and efficiency of your research with the PRKCA Monoclonal Antibody (CAB11107) from AssayGenie.
Product Name:
PKC alpha Rabbit Monoclonal Antibody
SKU:
CAB11107
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 573-672 of human PKC alpha (P17252).
Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. This kinase has been reported to play roles in many different cellular processes, such as cell adhesion, cell transformation, cell cycle checkpoint, and cell volume control. Knockout studies in mice suggest that this kinase may be a fundamental regulator of cardiac contractility and Ca(2+) handling in myocytes.
Purification Method:
Affinity purification
Gene ID:
5578
Clone Number:
ARC0197
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates using PKC alpha pAb (CAB11107) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
