PRKAG1 Rabbit Polyclonal Antibody (CAB7300)
- SKU:
- CAB7300
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Metabolism
Frequently bought together:
Description
Product Name: | PRKAG1 Rabbit Polyclonal Antibody |
SKU: | CAB7300 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-331 of human PRKAG1 (NP_002724.1). |
Sequence: | METV ISSD SSPA VENE HPQE TPES NNSV YTSF MKSH RCYD LIPT SSKL VVFD TSLQ VKKA FFAL VTNG VRAA PLWD SKKQ SFVG MLTI TDFI NILH RYYK SALV QIYE LEEH KIET WREV YLQD SFKP LVCI SPNA SLFD AVSS LIRN KIHR LPVI DPES GNTL YILT HKRI LKFL KLFI TEFP KPEF MSKS LEEL QIGT YANI AMVR TTTP VYVA LGIF VQHR VSAL PVVD EKGR VVDI YSKF DVIN LAAE KTYN NLDV SVTK ALQH RSHY FEGV LKCY LHET LETI INRL VEAE VHRL VVVD ENDV VKGI VSLS DILQ ALVL TGGE KKP |
Tested Applications: | WB IHC-P IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IHC-P,1:50 - 1:200 IF/ICC,1:50 - 1:100 |
Synonyms: | AMPKG; PRKAG1 |
Positive Sample: | Jurkat,22Rv1,Mouse kidney,Mouse thymus |
Conjugate: | Unconjugated |
Cellular Localization: | cytoplasm, cytosol, nucleoplasm, nucleus |
Calculated MW: | 38kDa |
Observed MW: | 36kDa/38kDa |
The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit is one of the gamma regulatory subunits of AMPK. Alternatively spliced transcript variants encoding distinct isoforms have been observed.
Purification Method: | Affinity purification |
Gene ID: | 5571 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |